Across TCGA pan-cancer cohorts, OR7L1P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of OR7L1P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR7L1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7L1P is over-expressed in tumor.
HNSC, LUAD, and LUSC are the cancer types where OR7L1P tumor–normal differential expression is most reproducible.