OR7G2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR7G2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR7G2-associated genes across cancer lineages are KRTAP19-3, SPACA5B, and ADIG. Each is linked with OR7G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7G2-to-partner and partner-to-OR7G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP19-3 grouped by OR7G2-low versus OR7G2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7G2→partner) and Y-score (partner→OR7G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaKRTAP19-3 →+0.236+4.807<.001.00631
LUNG_SCLCSPACA5B →+0.223+5.643<.001.00231
LUNG_SCLCADIG →+0.061+5.029<.001.00631
LARGE_INTESTINEMYH13 →+0.614+4.054<.001.00431
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

KRTAP19-3 by OR7G2 expression — BLOOD_Myeloma

Box plot of KRTAP19-3 in OR7G2-low vs OR7G2-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration