OR7G1

Across TCGA patient cohorts, OR7G1 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7G1-associated genes across cancer lineages are FASN, FOXO3a_pS318_S321, and GATA6. Each is linked with OR7G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7G1-to-partner and partner-to-OR7G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by OR7G1-low versus OR7G1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7G1→partner) and Y-score (partner→OR7G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.364	+1.700	.029	.044	3	2
UCEC	FOXO3a_pS318_S321 →	-0.146	-2.312	.005	.034	3	2
UCEC	GATA6 →	-0.222	-3.584	<.001	.002	3	2
UCEC	PCNA →	+0.270	+3.321	.003	.010	3	2
UCEC	Annexin-1 →	+0.669	+2.222	.002	.011	3	2
UCEC	STAT3_pY705 →	-0.395	-1.700	<.001	.044	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

FASN by OR7G1 expression — UCEC

Explore this box plot interactively →