Across TCGA pan-cancer cohorts, OR7E26P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR7E26P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where OR7E26P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR7E26P is over-expressed in tumor, although a few such as BRCA and PRAD show the opposite, repressed pattern.
THCA, BRCA, and COAD are the cancer types where OR7E26P tumor–normal differential expression is most reproducible.