OR7E24

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR7E24 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR7E24-associated genes across cancer lineages are CD5, OR51E1, and C11orf87. Each is linked with OR7E24 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7E24-to-partner and partner-to-OR7E24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD5 grouped by OR7E24-low versus OR7E24-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7E24→partner) and Y-score (partner→OR7E24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINCD5 →+0.055+3.626.001.00331
SKINOR51E1 →+0.019+3.378<.001.00131
SKINC11orf87 →+0.047+3.374<.001.00531
LARGE_INTESTINEMDGA2 →+0.220+3.854<.001.00631
LARGE_INTESTINEECE2 →+0.323+4.054<.001.00431
LARGE_INTESTINEMAGEB10 →+0.087+3.930<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CD5 by OR7E24 expression — SKIN

Box plot of CD5 in OR7E24-low vs OR7E24-high samples in SKIN.

Explore this box plot interactively →

Exploration