OR7E22P

Across TCGA pan-cancer cohorts, OR7E22P RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of OR7E22P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR7E22P RNA is repressed in tumor relative to normal tissue. In most cancer types OR7E22P is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KIRC, THCA, and UCEC are the cancer types where OR7E22P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR7E22P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	−0.102	<.001	11	view →
THCA	Male	III,IV	+0.218	<.001	9	view →
UCEC	All	II,III,IV	+1.575	<.001	6	view →
BRCA	Female	All	−0.769	<.001	6	view →
KICH	All	All	−0.120	.004	6	view →
LUAD	All	All	+0.479	<.001	5	view →
PAAD	All	All	+0.985	.007	2	view →
PRAD	All	All	−0.292	<.001	2	view →
LIHC	All	All	+0.038	.037	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

OR7E22P–KIRC

Open the KIRC breakdown →