Across TCGA pan-cancer cohorts, OR7E140P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR7E140P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where OR7E140P RNA is repressed in tumor relative to normal tissue. In most cancer types OR7E140P is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.
KICH and LUSC are the cancer types where OR7E140P tumor–normal differential expression is most reproducible.