OR7D4

Across TCGA patient cohorts, OR7D4 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR7D4-associated genes across cancer lineages are GATA3, PKC-a, and Stathmin. Each is linked with OR7D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7D4-to-partner and partner-to-OR7D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA3 grouped by OR7D4-low versus OR7D4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7D4→partner) and Y-score (partner→OR7D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GATA3 →	+0.169	+2.197	.043	.033	3	2
LUSC	PKC-a →	+0.201	+3.349	.042	.005	3	2
SKCM	Stathmin →	+0.224	+2.247	<.001	.005	3	2
LUSC	p38-MAPK →	-0.151	-2.986	.022	.035	3	1
LUSC	PKC-a_pS657 →	+0.258	+3.331	.008	.005	3	1
LUSC	4E-BP1_pS65 →	+0.201	+2.179	.010	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

GATA3 by OR7D4 expression — LUSC

Explore this box plot interactively →