Across TCGA patient cohorts, OR7D2 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7D2-associated genes across cancer lineages are PCNA, PDCD4, and c-Jun_pS73. Each is linked with OR7D2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR7D2-to-partner and partner-to-OR7D2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7D2→partner) and Y-score (partner→OR7D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.211	+2.000	.003	.009	3	3
COAD	PDCD4 →	-0.593	-3.450	.001	.005	3	2
COAD	c-Jun_pS73 →	-0.200	-2.279	.005	.035	3	2
COAD	4E-BP1 →	+0.329	+3.321	<.001	.009	3	2
UCEC	ERK2 →	+0.222	+3.906	<.001	<.001	3	2
UCEC	MEK1 →	+0.535	+3.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

OR7D2 survival (RNA) · tumor vs normal (RNA) · all OR7D2 data types