Across TCGA patient cohorts, OR7A5 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7A5-associated genes across cancer lineages are c-Met_pY1235, FOXO3a_pS318_S321, and Ku80. Each is linked with OR7A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7A5-to-partner and partner-to-OR7A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7A5→partner) and Y-score (partner→OR7A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	c-Met_pY1235 →	+0.104	+3.321	.007	.010	3	2
UCEC	FOXO3a_pS318_S321 →	-0.216	-3.160	<.001	.019	3	1
UCEC	Ku80 →	+0.261	+3.335	.034	.005	3	1
UCEC	p62 Lck ligand →	+0.612	+3.009	<.001	.019	3	1
UCEC	Rab25 →	-0.571	-3.000	<.001	.036	3	1
UCEC	Src_pY416 →	-0.290	-3.143	.021	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

OR7A5 survival (RNA) · tumor vs normal (RNA) · all OR7A5 data types