OR7A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR7A5 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR7A5-associated genes across cancer lineages are PHOX2B, OR11H1, and SLCO1C1. Each is linked with OR7A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7A5-to-partner and partner-to-OR7A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7A5→partner) and Y-score (partner→OR7A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPHOX2B →+0.022+4.365<.001.00231
BLOOD_LeukemiaOR11H1 →+0.089+6.201<.001<.00131
BLOOD_LeukemiaSLCO1C1 →+0.076+3.705<.001.00731
BLOOD_LeukemiaARHGAP36 →+0.022+3.944<.001.00631
BLOOD_LeukemiaLYZL4 →+0.077+4.567<.001.00131
BLOOD_LeukemiaOR4K2 →+0.025+4.384<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

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