OR7A17

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR7A17 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR7A17-associated genes across cancer lineages are INPP4B, JNK2, and p38-MAPK_pT180_Y182. Each is linked with OR7A17 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR7A17-to-partner and partner-to-OR7A17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR7A17→partner) and Y-score (partner→OR7A17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.437-3.169.007.01831
UCECJNK2 →+0.349+2.834<.001.03431
UCECp38-MAPK_pT180_Y182 →-0.460-2.308.042.03631
UCECPCNA →+0.315+2.321.003.03531
UCECSTAT3_pY705 →-0.557-3.321<.001.00931
UCECTuberin →+0.385+2.321.004.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration