Across TCGA patient cohorts, OR6X1 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6X1-associated genes across cancer lineages are Caspase-7-cleavedD198, FOXO3a_pS318_S321, and eEF2. Each is linked with OR6X1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6X1-to-partner and partner-to-OR6X1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6X1→partner) and Y-score (partner→OR6X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.687	+3.189	.010	.010	3	3
UCEC	FOXO3a_pS318_S321 →	-0.149	-2.449	.008	.019	3	2
UCEC	eEF2 →	+0.469	+3.807	.003	<.001	3	1
UCEC	EGFR_pY1068 →	-0.385	-3.807	<.001	<.001	3	1
UCEC	A-Raf_pS299 →	-0.135	-2.000	.012	.032	3	1
UCEC	GAPDH →	+0.601	+3.807	.013	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

OR6X1 survival (RNA) · tumor vs normal (RNA) · all OR6X1 data types