OR6T1

Across TCGA cell cohorts, OR6T1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR6T1-associated genes across cancer lineages are OPN1MW2, DCANP1, and SMIM36. Each is linked with OR6T1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6T1-to-partner and partner-to-OR6T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW2 grouped by OR6T1-low versus OR6T1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6T1→partner) and Y-score (partner→OR6T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OPN1MW2 →	+0.382	+4.058	<.001	.007	3	1
LUNG_SCLC	DCANP1 →	+0.012	+4.256	<.001	.002	3	1
LUNG_SCLC	SMIM36 →	+0.538	+3.898	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OPN1MW2 by OR6T1 expression — LUNG_SCLC

Explore this box plot interactively →