Across TCGA pan-cancer cohorts, OR6R1P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of OR6R1P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where OR6R1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR6R1P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where OR6R1P tumor–normal differential expression is most reproducible.