OR6Q1

Across TCGA patient cohorts, OR6Q1 mutation is significantly associated with the RNA expression of many other genes, with 1,742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6Q1-associated genes across cancer lineages are LINC00294, LYPLA1P1, and ZNF74. Each is linked with OR6Q1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6Q1-to-partner and partner-to-OR6Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00294 grouped by OR6Q1-low versus OR6Q1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6Q1→partner) and Y-score (partner→OR6Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00294 →	+0.492	+3.021	.002	<.001	3	2
HNSC	LYPLA1P1 →	+0.069	+5.912	<.001	.002	3	2
UCEC	ZNF74 →	+0.559	+3.601	<.001	.001	3	2
UCEC	PRKN →	-0.461	-3.660	.002	.001	3	2
UCEC	PLEKHG7 →	-0.629	-2.311	.003	.006	3	2
UCEC	E2F4 →	+0.500	+3.733	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,742 associations by consensus.

LINC00294 by OR6Q1 expression — UCEC

Explore this box plot interactively →