OR6Q1

Across TCGA patient cohorts, OR6Q1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6Q1-associated genes across cancer lineages are Annexin-1, EGFR_pY1068, and FASN. Each is linked with OR6Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6Q1-to-partner and partner-to-OR6Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by OR6Q1-low versus OR6Q1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6Q1→partner) and Y-score (partner→OR6Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.761	+3.479	.001	.002	3	2
UCEC	EGFR_pY1068 →	-0.224	-2.000	.047	.032	3	1
UCEC	FASN →	+0.361	+2.700	.042	.006	3	1
UCEC	FOXO3a_pS318_S321 →	-0.120	-2.449	.033	.019	3	1
UCEC	JNK2 →	+0.218	+2.000	.014	.032	3	1
UCEC	Ku80 →	+0.302	+2.713	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Annexin-1 by OR6Q1 expression — UCEC

Explore this box plot interactively →