OR6Q1

Across TCGA cell cohorts, OR6Q1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR6Q1-associated genes across cancer lineages are TNP1, TAS2R9, and TAAR8. Each is linked with OR6Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6Q1-to-partner and partner-to-OR6Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by OR6Q1-low versus OR6Q1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6Q1→partner) and Y-score (partner→OR6Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TNP1 →	+0.327	+4.981	<.001	.008	3	1
LUNG_NSCLC_LUAD	TAS2R9 →	+0.057	+3.925	<.001	.005	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	RGR →	+0.013	+4.481	.001	.001	3	1
LUNG_NSCLC_LUAD	OR2V2 →	+0.036	+4.959	<.001	<.001	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.031	+4.813	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TNP1 by OR6Q1 expression — CNS

Explore this box plot interactively →