Across TCGA patient cohorts, OR6N2 mutation is significantly associated with the RNA expression of many other genes, with 2,948 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6N2-associated genes across cancer lineages are FOXK2, NKIRAS2, and NSUN2. Each is linked with OR6N2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR6N2-to-partner and partner-to-OR6N2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6N2→partner) and Y-score (partner→OR6N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXK2 →	+0.426	+2.042	<.001	.005	3	4
UCEC	NKIRAS2 →	+0.406	+2.748	.001	.003	3	3
UCEC	NSUN2 →	+0.461	+3.507	.002	.002	3	3
UCEC	GOLGA3 →	+0.700	+3.191	<.001	<.001	3	3
BLCA	HMGB1P32 →	+0.116	+5.329	<.001	.006	3	3
UCEC	RNA5SP412 →	+0.465	+2.074	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,948 associations by consensus.

Exploration

OR6N2 survival (RNA) · tumor vs normal (RNA) · all OR6N2 data types