OR6N2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6N2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6N2-associated genes across cancer lineages are JNK_pT183_Y185, Cyclin-B1, and Shc_pY317. Each is linked with OR6N2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6N2-to-partner and partner-to-OR6N2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6N2→partner) and Y-score (partner→OR6N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADJNK_pT183_Y185 →-0.161-3.169.037.01932
LUADCyclin-B1 →+0.760+3.000.002.03532
UCECShc_pY317 →-0.155-1.700.016.04432
LUADFoxM1 →+0.343+2.840.010.03331
LUADGSK-3a-b_pS21_S9 →+0.423+3.000.023.03531
LUADMSH6 →+0.505+3.016.001.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

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