Across TCGA patient cohorts, OR6M1 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6M1-associated genes across cancer lineages are FoxM1, p38-MAPK_pT180_Y182, and PCNA. Each is linked with OR6M1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6M1-to-partner and partner-to-OR6M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6M1→partner) and Y-score (partner→OR6M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.275	+3.807	.018	<.001	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.675	-3.459	<.001	.005	3	2
UCEC	PCNA →	+0.248	+2.700	.010	.006	3	2
UCEC	VHL →	-1.149	-1.874	<.001	.049	3	2
UCEC	cIAP →	+0.151	+2.727	.014	.003	3	2
UCEC	Cyclin-B1 →	+1.039	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

OR6M1 survival (RNA) · tumor vs normal (RNA) · all OR6M1 data types