Across TCGA cell cohorts, OR6M1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR6M1-associated genes across cancer lineages are DEFB125, H2BW1, and ZAN. Each is linked with OR6M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6M1-to-partner and partner-to-OR6M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6M1→partner) and Y-score (partner→OR6M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DEFB125 →	+0.086	+5.643	<.001	.002	3	1
LUNG_NSCLC_LUAD	H2BW1 →	+0.470	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	ZAN →	+0.004	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	CST9 →	+0.087	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	NAT8B →	+0.042	+4.371	.005	.005	3	1
LUNG_NSCLC_LUAD	OR1D4 →	+0.039	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

OR6M1 survival (RNA) · tumor vs normal (RNA) · all OR6M1 data types