OR6K3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6K3 mutation is significantly associated with the immune_cell of many other genes, with 9 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR6K3-associated genes across cancer lineages are CD4+ Tem, HSC, and mv Endothelial cells. Each is linked with OR6K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6K3-to-partner and partner-to-OR6K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K3→partner) and Y-score (partner→OR6K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCCD4+ Tem →+0.001+6.174.001.02031
SKCMHSC →-0.081-2.700.005.00622
SKCMmv Endothelial cells →-0.021-1.941.025.03131
SKCMSmooth muscle →+0.100+1.899.010.02831
LUSCBasophils →+0.160+2.584.005.01131
LUSCNKT →-0.070-3.459.015.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration