Across TCGA cell cohorts, OR6K3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR6K3-associated genes across cancer lineages are TPD52L3, OR4C46, and MBD3L1. Each is linked with OR6K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6K3-to-partner and partner-to-OR6K3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K3→partner) and Y-score (partner→OR6K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TPD52L3 →	+0.316	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR4C46 →	+0.012	+4.681	<.001	.003	3	1
SKIN	MBD3L1 →	+0.014	+3.700	<.001	.009	3	1
SKIN	SLC2A7 →	+0.023	+3.103	<.001	.004	3	1
SKIN	ZSCAN5C →	+0.033	+3.714	<.001	.004	3	1
LARGE_INTESTINE	MAGEB4 →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

OR6K3 survival (RNA) · tumor vs normal (RNA) · all OR6K3 data types