Across TCGA patient cohorts, OR6K2 mutation is significantly associated with the RNA expression of many other genes, with 3,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6K2-associated genes across cancer lineages are TIPIN, C18orf21, and TYMS. Each is linked with OR6K2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR6K2-to-partner and partner-to-OR6K2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K2→partner) and Y-score (partner→OR6K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIPIN →	+0.564	+2.944	<.001	<.001	3	4
COAD	C18orf21 →	+0.582	+3.389	<.001	.004	3	4
SKCM	TYMS →	+0.564	+2.462	.006	<.001	3	4
UCEC	VPS37A →	+0.529	+2.807	.002	.003	3	4
UCEC	SLBP →	+0.463	+2.732	.009	.003	3	4
UCEC	ATF4 →	+0.526	+2.233	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,329 associations by consensus.

Exploration

OR6K2 survival (RNA) · tumor vs normal (RNA) · all OR6K2 data types