OR6K2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6K2 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6K2-associated genes across cancer lineages are 4E-BP1, mTOR_pS2448, and p90 RSK_pT359_S363. Each is linked with OR6K2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OR6K2-to-partner and partner-to-OR6K2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6K2→partner) and Y-score (partner→OR6K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COAD4E-BP1 →+0.324+3.178.002.01025
UCECmTOR_pS2448 →-0.121-3.308.048.00933
LUADp90 RSK_pT359_S363 →-0.181-3.169.013.01832
UCECMEK1 →+0.471+2.700.001.00632
COADEGFR_pY1068 →-0.377-3.161.019.01932
SKCMBim →+0.228+2.000.032.02932
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

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