OR6J1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR6J1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR6J1-associated genes across cancer lineages are ADAM30, HMHB1, and CCL13. Each is linked with OR6J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6J1-to-partner and partner-to-OR6J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM30 grouped by OR6J1-low versus OR6J1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6J1→partner) and Y-score (partner→OR6J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADADAM30 →+0.006+4.212.008.00731
LUNG_NSCLC_LUADHMHB1 →+0.064+4.662<.001.00531
LUNG_NSCLC_LUADCCL13 →+0.034+4.662<.001.00531
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ADAM30 by OR6J1 expression — LUNG_NSCLC_LUAD

Box plot of ADAM30 in OR6J1-low vs OR6J1-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration