Across TCGA patient cohorts, OR6C74 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C74-associated genes across cancer lineages are ASNS, ATM, and ACC_pS79. Each is linked with OR6C74 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6C74-to-partner and partner-to-OR6C74 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C74→partner) and Y-score (partner→OR6C74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.550	+2.321	.001	.033	3	2
UCEC	ATM →	-0.435	-3.000	.039	.036	3	2
SKCM	ACC_pS79 →	+0.311	+3.321	.016	.009	3	2
SKCM	GAPDH →	+0.588	+3.000	.025	.035	2	3
UCEC	EGFR_pY1068 →	-0.275	-2.999	.018	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.166	-2.999	.034	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

OR6C74 survival (RNA) · tumor vs normal (RNA) · all OR6C74 data types