Across TCGA cell cohorts, OR6C74 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR6C74-associated genes across cancer lineages are ZAN, SEPTIN14, and CASP12. Each is linked with OR6C74 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C74-to-partner and partner-to-OR6C74 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C74→partner) and Y-score (partner→OR6C74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZAN →	+0.014	+4.882	<.001	<.001	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.009	+3.684	<.001	.006	3	1
LARGE_INTESTINE	CASP12 →	+0.033	+3.684	<.001	.006	3	1
LARGE_INTESTINE	OR2J1 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TEX53 →	+0.074	+3.684	.006	.006	3	1
LARGE_INTESTINE	OR6J1 →	+0.009	+3.920	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OR6C74 survival (RNA) · tumor vs normal (RNA) · all OR6C74 data types