Across TCGA patient cohorts, OR6C70 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C70-associated genes across cancer lineages are PREX1, S6, and 4E-BP1_pS65. Each is linked with OR6C70 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C70-to-partner and partner-to-OR6C70 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C70→partner) and Y-score (partner→OR6C70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PREX1 →	-0.298	-3.169	.022	.017	3	1
SKCM	S6 →	-0.474	-2.321	.008	.032	3	1
SKCM	4E-BP1_pS65 →	+0.211	+2.597	.008	.005	3	1
SKCM	Claudin-7 →	-0.122	-1.872	.041	.016	3	1
UCEC	EGFR_pY1068 →	-0.314	-3.000	.022	.036	3	1
UCEC	p70-S6K_pT389 →	-0.247	-3.169	.017	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

OR6C70 survival (RNA) · tumor vs normal (RNA) · all OR6C70 data types