Across TCGA patient cohorts, OR6C68 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C68-associated genes across cancer lineages are FoxM1, GSK-3_pS9, and PKC-b-II_pS660. Each is linked with OR6C68 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C68-to-partner and partner-to-OR6C68 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C68→partner) and Y-score (partner→OR6C68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.336	+2.817	.024	.036	3	1
UCEC	GSK-3_pS9 →	-0.615	-3.000	.008	.036	3	1
UCEC	PKC-b-II_pS660 →	-0.363	-3.000	.023	.037	3	1
UCEC	Beclin →	+0.119	+3.000	.029	.036	3	1
UCEC	c-Met_pY1235 →	+0.090	+2.817	.035	.036	3	1
SKCM	AMPK_pT172 →	+0.370	+3.000	.049	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

OR6C68 survival (RNA) · tumor vs normal (RNA) · all OR6C68 data types