Across TCGA patient cohorts, OR6C65 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C65-associated genes across cancer lineages are Caspase-8, Annexin-1, and CDK1_pY15. Each is linked with OR6C65 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C65-to-partner and partner-to-OR6C65 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C65→partner) and Y-score (partner→OR6C65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-8 →	-0.238	-2.973	.025	.035	3	2
SKCM	Annexin-1 →	+0.437	+1.584	.015	.035	3	1
SKCM	CDK1_pY15 →	+0.290	+1.751	.025	.048	3	1
UCEC	eIF4E →	+0.184	+3.459	.040	.005	2	2
UCEC	MEK1 →	+0.562	+3.700	<.001	.001	3	1
UCEC	Rab25 →	-0.279	-2.999	.047	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

OR6C65 survival (RNA) · tumor vs normal (RNA) · all OR6C65 data types