Across TCGA patient cohorts, OR6C6 mutation is significantly associated with the RNA expression of many other genes, with 879 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C6-associated genes across cancer lineages are RPL23AP4, ZDHHC12, and CIAO2B. Each is linked with OR6C6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C6-to-partner and partner-to-OR6C6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C6→partner) and Y-score (partner→OR6C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RPL23AP4 →	+0.171	+5.039	<.001	.008	3	2
UCEC	ZDHHC12 →	+0.493	+3.470	.004	.002	3	2
UCEC	CIAO2B →	+0.457	+2.828	.003	.001	3	2
UCEC	URM1 →	+0.421	+3.329	.003	.005	3	2
UCEC	NUDCD2 →	+0.468	+2.828	.009	.001	3	2
SKCM	ZBTB8OS →	+0.435	+2.106	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 879 associations by consensus.

Exploration

OR6C6 survival (RNA) · tumor vs normal (RNA) · all OR6C6 data types