Across TCGA patient cohorts, OR6C3 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR6C3-associated genes across cancer lineages are Class-switched memory B-cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with OR6C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C3-to-partner and partner-to-OR6C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C3→partner) and Y-score (partner→OR6C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Class-switched memory B-cells →	-0.033	-1.906	.049	.024	3	1
SKCM	Endothelial cells →	-0.034	-1.759	.019	.014	3	1
SKCM	lymphatic Endothelial cells →	-0.017	-2.618	.038	<.001	3	1
SKCM	mv Endothelial cells →	-0.024	-2.163	.016	.003	3	1
SKCM	Plasma cells →	-0.016	-2.446	.025	.010	3	1
COAD	Monocytes →	+0.048	+5.734	<.001	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

OR6C3 survival (RNA) · tumor vs normal (RNA) · all OR6C3 data types