Across TCGA cell cohorts, OR6C3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR6C3-associated genes across cancer lineages are ASPA, IL2, and KCNK17. Each is linked with OR6C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C3-to-partner and partner-to-OR6C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C3→partner) and Y-score (partner→OR6C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ASPA →	+0.341	+4.137	.005	<.001	3	1
LARGE_INTESTINE	IL2 →	+0.034	+3.700	<.001	.009	3	1
LARGE_INTESTINE	KCNK17 →	+0.067	+3.906	<.001	.002	3	1
LARGE_INTESTINE	NAT8 →	+0.529	+3.546	.006	.004	3	1
LARGE_INTESTINE	BMP3 →	+0.416	+3.617	.004	.004	3	1
LARGE_INTESTINE	OR2B2 →	+0.026	+3.669	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

OR6C3 survival (RNA) · tumor vs normal (RNA) · all OR6C3 data types