OR6C2

Across TCGA patient cohorts, OR6C2 mutation is significantly associated with the RNA expression of many other genes, with 934 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR6C2-associated genes across cancer lineages are RNU6-927P, RNA5SP443, and AZI2. Each is linked with OR6C2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6C2-to-partner and partner-to-OR6C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-927P grouped by OR6C2-low versus OR6C2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C2→partner) and Y-score (partner→OR6C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-927P →	+0.461	+5.103	<.001	.008	3	3
BLCA	RNA5SP443 →	+0.451	+5.329	<.001	.006	3	2
UCEC	AZI2 →	+0.687	+3.210	.001	.009	3	2
UCEC	ALKBH5 →	+0.546	+3.242	.006	.009	3	2
UCEC	TMEM38B →	+0.865	+3.332	.002	.005	3	2
CESC	HMGB4 →	+0.015	+5.306	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 934 associations by consensus.

RNU6-927P by OR6C2 expression — CESC

Explore this box plot interactively →