OR6C2

Across TCGA cell cohorts, OR6C2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR6C2-associated genes across cancer lineages are GGTLC2, SLC22A7, and TRIM49B. Each is linked with OR6C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6C2-to-partner and partner-to-OR6C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGTLC2 grouped by OR6C2-low versus OR6C2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C2→partner) and Y-score (partner→OR6C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GGTLC2 →	+0.030	+3.688	<.001	.002	3	1
SKIN	SLC22A7 →	+0.018	+4.022	<.001	.006	3	1
SKIN	TRIM49B →	+0.106	+3.845	.002	.003	3	1
SKIN	IL31 →	+0.021	+3.977	<.001	.001	3	1
SKIN	OR2J2 →	+0.008	+3.977	<.001	.001	3	1
SKIN	BPIFB2 →	+0.053	+3.554	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GGTLC2 by OR6C2 expression — SKIN

Explore this box plot interactively →