Across TCGA pan-cancer cohorts, OR6C1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR6C1 data layer compared with 8 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher OR6C1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR6C1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

THYM, STAD, and UCEC are the cancer types where OR6C1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
STAD	OS	Median	IV	0.001	0.544	<.001	12	view →
UCEC	DFS	Median	All	1.000	0.631	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR6C1 tumor-vs-normal RNA expression · all OR6C1 data types