Across TCGA patient cohorts, OR6C1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6C1-associated genes across cancer lineages are PCNA, Caspase-7-cleavedD198, and Cyclin-E2. Each is linked with OR6C1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6C1-to-partner and partner-to-OR6C1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6C1→partner) and Y-score (partner→OR6C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.285	+3.321	.003	.010	3	3
UCEC	Caspase-7-cleavedD198 →	+0.615	+2.827	.021	.035	3	2
UCEC	Cyclin-E2 →	+0.152	+1.884	.046	.030	3	2
COAD	GAPDH →	+0.622	+2.815	.025	.036	3	2
COAD	ASNS →	+0.952	+2.815	<.001	.036	3	2
UCEC	FOXO3a_pS318_S321 →	-0.130	-2.999	.020	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

OR6C1 survival (RNA) · tumor vs normal (RNA) · all OR6C1 data types