OR6B1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6B1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6B1-associated genes across cancer lineages are ERK2, p38-MAPK_pT180_Y182, and STAT3_pY705. Each is linked with OR6B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6B1-to-partner and partner-to-OR6B1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6B1→partner) and Y-score (partner→OR6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECERK2 →+0.239+2.415.002.00332
UCECp38-MAPK_pT180_Y182 →-0.537-2.115.002.01732
UCECSTAT3_pY705 →-0.265-2.321.012.03332
SKCMStathmin →+0.161+1.725.018.02432
SKCMCyclin-E2 →+0.150+2.087.017.00532
LUADEGFR_pY1068 →-0.575-3.000.021.03522
Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration