Across TCGA cell cohorts, OR6B1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OR6B1-associated genes across cancer lineages are MRGPRG, OR56A4, and OR2W1. Each is linked with OR6B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6B1-to-partner and partner-to-OR6B1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6B1→partner) and Y-score (partner→OR6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MRGPRG →	+0.029	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR56A4 →	+0.219	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR2W1 →	+0.032	+4.662	<.001	.005	3	1
CNS	TTLL2 →	+0.174	+3.736	<.001	.009	3	1
CNS	ADGRE3 →	+0.033	+4.044	<.001	.003	3	1
CNS	OR4D1 →	+0.056	+3.874	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

OR6B1 survival (RNA) · tumor vs normal (RNA) · all OR6B1 data types