OR6A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR6A2 mutation is significantly associated with the RNA expression of many other genes, with 2,546 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6A2-associated genes across cancer lineages are RNA5SP158, CLSPN, and FANCE. Each is linked with OR6A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6A2-to-partner and partner-to-OR6A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6A2→partner) and Y-score (partner→OR6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP158 →+0.134+3.312<.001.00333
UCECCLSPN →+0.976+3.016<.001<.00133
LUADFANCE →+0.881+3.223<.001.00933
UCECE2F1 →+0.947+3.861<.001<.00133
UCECADNP2 →+0.553+1.869.001.00533
UCECMTCH2 →+0.442+2.769.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,546 associations by consensus.

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