Across TCGA patient cohorts, OR6A2 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR6A2-associated genes across cancer lineages are TFRC, Chk2, and PDCD4. Each is linked with OR6A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR6A2-to-partner and partner-to-OR6A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6A2→partner) and Y-score (partner→OR6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.685	+3.584	.001	.002	3	3
SKCM	Chk2 →	+0.256	+3.000	.017	.035	3	2
UCEC	PDCD4 →	-0.437	-3.169	.024	.018	3	2
UCEC	Annexin-1 →	+0.632	+2.479	.003	.010	3	2
SKCM	ASNS →	+0.462	+2.459	.026	.020	3	1
UCEC	EGFR_pY1068 →	-0.249	-3.321	.016	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

OR6A2 survival (RNA) · tumor vs normal (RNA) · all OR6A2 data types