Across TCGA cell cohorts, OR6A2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR6A2-associated genes across cancer lineages are ACTL9, MAGEB18, and KIR2DL4. Each is linked with OR6A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR6A2-to-partner and partner-to-OR6A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR6A2→partner) and Y-score (partner→OR6A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ACTL9 →	+0.313	+4.930	<.001	.008	3	2
LUNG_SCLC	MAGEB18 →	+0.012	+4.269	.009	.005	3	1
LUNG_SCLC	KIR2DL4 →	+0.270	+4.817	<.001	.001	3	1
LUNG_SCLC	OR5H2 →	+0.037	+4.643	<.001	.004	3	1
LUNG_SCLC	ASIC5 →	+0.070	+4.269	.001	.005	3	1
LUNG_SCLC	CD300H →	+0.118	+5.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

OR6A2 survival (RNA) · tumor vs normal (RNA) · all OR6A2 data types