OR5V1

Across TCGA cell cohorts, OR5V1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR5V1-associated genes across cancer lineages are PIWIL3, ARMS2, and CABP2. Each is linked with OR5V1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5V1-to-partner and partner-to-OR5V1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIWIL3 grouped by OR5V1-low versus OR5V1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5V1→partner) and Y-score (partner→OR5V1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PIWIL3 →	+0.021	+4.054	.008	.004	3	1
LARGE_INTESTINE	ARMS2 →	+0.134	+3.938	.009	.005	3	1
LUNG_SCLC	CABP2 →	+0.075	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PIWIL3 by OR5V1 expression — LARGE_INTESTINE

Explore this box plot interactively →