OR5T3

Across TCGA patient cohorts, OR5T3 mutation is significantly associated with the RNA expression of many other genes, with 1,820 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5T3-associated genes across cancer lineages are TOMM22P5, AUP1, and RTF2. Each is linked with OR5T3 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5T3-to-partner and partner-to-OR5T3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOMM22P5 grouped by OR5T3-low versus OR5T3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T3→partner) and Y-score (partner→OR5T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOMM22P5 →	+0.190	+2.061	.001	.001	3	3
SKCM	AUP1 →	+0.297	+2.006	.001	.001	3	3
SKCM	RTF2 →	+0.286	+3.510	.006	.002	3	3
UCEC	HSD17B10 →	+0.408	+2.169	.003	.003	3	3
UCEC	POLR2G →	+0.425	+2.716	.001	<.001	3	3
LUAD	CENPX →	+0.613	+2.611	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,820 associations by consensus.

TOMM22P5 by OR5T3 expression — UCEC

Explore this box plot interactively →