OR5T3

Across TCGA cell cohorts, OR5T3 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5T3-associated genes across cancer lineages are SERPINA12, OPRPN, and USP17L3. Each is linked with OR5T3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5T3-to-partner and partner-to-OR5T3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA12 grouped by OR5T3-low versus OR5T3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T3→partner) and Y-score (partner→OR5T3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	SERPINA12 →	+0.016	+5.614	<.001	.002	3	2
PANCREAS	OPRPN →	+0.029	+5.000	<.001	.006	3	1
PANCREAS	USP17L3 →	+0.016	+5.000	<.001	.006	3	1
BREAST	OR10A5 →	+0.028	+5.169	<.001	.005	3	1
BREAST	OR6K2 →	+0.023	+5.781	<.001	.001	3	1
LARGE_INTESTINE	ECE2 →	+0.319	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

SERPINA12 by OR5T3 expression — PANCREAS

Explore this box plot interactively →