OR5T1

Across TCGA patient cohorts, OR5T1 mutation is significantly associated with the RNA expression of many other genes, with 3,022 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5T1-associated genes across cancer lineages are RNASEH2A, CARS1, and AUP1. Each is linked with OR5T1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5T1-to-partner and partner-to-OR5T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH2A grouped by OR5T1-low versus OR5T1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T1→partner) and Y-score (partner→OR5T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNASEH2A →	+0.586	+3.889	.005	<.001	3	3
UCEC	CARS1 →	+0.537	+2.010	<.001	.001	3	3
SKCM	AUP1 →	+0.331	+2.006	<.001	.001	3	3
UCEC	TOMM40 →	+0.369	+2.403	.006	<.001	3	3
SKCM	RBM17 →	+0.327	+2.018	.008	.005	3	3
UCEC	YARS1 →	+0.541	+2.053	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,022 associations by consensus.

RNASEH2A by OR5T1 expression — LUAD

Explore this box plot interactively →