OR5T1

Across TCGA patient cohorts, OR5T1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5T1-associated genes across cancer lineages are PDCD4, MIG-6, and MAPK_pT202_Y204. Each is linked with OR5T1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR5T1-to-partner and partner-to-OR5T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by OR5T1-low versus OR5T1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T1→partner) and Y-score (partner→OR5T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PDCD4 →	-0.523	-2.321	.001	.033	3	3
SKCM	MIG-6 →	+0.141	+2.195	.031	.032	3	3
LUAD	MAPK_pT202_Y204 →	-0.477	-3.321	.011	.010	3	2
LUAD	mTOR_pS2448 →	-0.300	-3.309	.001	.009	3	2
SKCM	Tuberin_pT1462 →	-0.256	-1.807	.026	.026	3	2
LUAD	Bap1-c-4 →	+0.246	+2.186	.009	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

PDCD4 by OR5T1 expression — SKCM

Explore this box plot interactively →