OR5T1

Across TCGA cell cohorts, OR5T1 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5T1-associated genes across cancer lineages are CCL19, SCRT2, and TOPAZ1. Each is linked with OR5T1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5T1-to-partner and partner-to-OR5T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL19 grouped by OR5T1-low versus OR5T1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5T1→partner) and Y-score (partner→OR5T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCL19 →	+0.056	+3.887	.001	.002	3	2
LUNG_NSCLC_LUAD	SCRT2 →	+0.033	+4.082	.004	.001	3	2
LARGE_INTESTINE	TOPAZ1 →	+0.019	+4.415	<.001	.007	3	1
LARGE_INTESTINE	TP53TG3E →	+0.016	+4.930	<.001	.001	3	1
CNS	TAS2R7 →	+0.018	+4.981	.003	.008	3	1
CNS	HTR3D →	+1.538	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

CCL19 by OR5T1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →